Yes! Wonderful Napa, where the roads are winding and the wine stops are plentiful.
Bus tour is a must! Enjoy the ride and leave the driving to someone else. This way you can fully experience the offerings. There are literally wineries on both sides of the road and every 5 minutes or so. Plan to spend at least a full day touring this way. 3 nights/days in the region would be better.
You could stay in the town of Napa itself. (Yes!! Do it, if it’s in budget.) Then, in my order of opinion, American Canyon (because it’s super easy and just minutes from Napa on the right highway), Calistoga because it’s quaint & in the centre of many wineries, Fulton, Santa Rosa, or Novato. Planning to go in/out of San Francisco or the Bay Area will cost you 2 hours in each direction, plus bridge tolls.
There are wine tastings in castles, in (former) gas stations, in cellars, a former National Bank, in mini-mall settings, and everywhere in between.
We did a self-guided tour of Castello di Amorosa. An Italian style renaissance castle just about 5 minutes east of Calistoga.
Calistoga itself is a beautiful, quaint town. A former bank on Main Street has been turned into a fabulous wine tasting venue.
In terms of wine tasting cost, if you are just popping in (not part of a prepaid tour) expect to pay at least $20+ per person per flight of wines. More for premium selections. More for a tour plus tasting. For example Castello di Amorosa in the self-guided version was $30 & tax. ($32.73). Entry for children ages 5-20 were $20 & tax. The guided tour was $65 & up.
There is a wine train that leaves the town of Napa itself. I think it was about $200 a person. Definitely look it up. If it fits your schedule it would be an enviable way to travel & fully enjoy the region.
The wine itself, expect to pay a minimum of $30 per bottle for anything in this region, and $300 or so for special bottles, and of course, there will be even more expensive specialty bottles for collectors.
Most wineries seem to have a “Wine Club” with exclusive invitations to specialty tastings, dinners and events. Standard buy in to the club, seemed to be at least the purchase of a case of wine, or $500.
Monthly winery subscriptions were also advertised often. Shipping included, in USA of course. Like a Netflix subscription they’d just keep charging your credit card & sending the wine until you stop payment.
When you’re in Napa, there’s one more thing to do… announce you’re in Napa by taking a photo at the roadside sign! There’s a pull off big enough for 6 tour buses and I expect most bus tours DO stop at the sign for a selfie and fresh air break.